Academic article
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Joseph M. Rutkowski; Carl Erik Markhus; Christina Gyenge
et al. (2010). Dermal collagen and lipid deposition correlate with tissue swelling and hydraulic conductivity in murine primary lymphedema. (external link)
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Knut Aukland; Rolf Kåre Reed; Helge Wiig
(1997). The problem of gaining access to interstitial fluid. An attempt to rationalize a wicked discussion on wicks. (external link)
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Linda Elin Birkhaug Stuhr; Ingrid Moen; Torbjørn Nedrebø
et al. (2008). Peritumoral TNFalpha administration influences tumor stroma structure and physiology independently of growth in DMBA-induced mammary tumours. (external link)
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Panagiota Papadakou; Tine Veronica Karlsen; Helge Wiig
et al. (2015). Determination of lymph flow in murine oral mucosa using depot clearance of near-infrared-labeled albumin. (external link)
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Knut Aukland; Helge Wiig; Olav Tenstad
et al. (1997). Interstitial exclusion of macromolecules studied by graded centrifugation. (external link)
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Marianne Muller Indrebø; Ansgar Berg; Henrik Holmstrøm
et al. (2017). Fluid accumulation after closure of atrial septal defects: the role of colloid osmotic pressure. (external link)
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Tine Veronica Karlsen; Elham Nikpey; Jianhua Han
et al. (2018). High-Salt Diet Causes Expansion of the Lymphatic Network
and Increased Lymph Flow in Skin and Muscle of Rats. (external link)
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Linda Elin Birkhaug Stuhr; Ingrid Moen; Torbjørn Nedrebø
et al. (2008). Peritumoral TNF alpha administration influences tumour stroma structure and physiology independently of growth in DMBA-induced mammary tumours. (external link)
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Hans Jørgen Timm Guthe; Torbjørn Nedrebø; Olav Tenstad
et al. (2012). Effect of topical anaesthetics on interstitial colloid osmotic pressure in human subcutaneous tissue sampled by wick technique. (external link)
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Helge Wiig; D Keskin; Raghu Kalluri
(2010). Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis og lymphatic function. (external link)
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Helge Wiig; L. Sibley; M. Decarlo
et al. (1991). Sampling interstitial fluid from rat skeletal muscle by intermuscular wicks. (external link)
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Helge Wiig; Per Ole Iversen
(2005). Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis. (external link)
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Laonard M. Ebah; Helge Wiig; Idalia Dawidowska
et al. (2013). Subcutaneous interstitial pressure and volume characteristics in renal impairment associated with edema. (external link)
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Daniela Negrini; Alberto Passi; Katia Bertin
et al. (2001). Isolation of pulmonary interstitial fluid in rabbits by a modified wick technique. (external link)
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Helge Wiig; Olav Tenstad
(2001). Interstitial exclusion of positively and negatively charged IgG in rat skin and muscle. (external link)
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Jaehwa Choi; Kimberly Credit; Karla Henderson
et al. (2006). Intraperitoneal immunotherapy for metastatic ovarian carcinoma: Resistance of intratumoral collagen to antibody penetration. (external link)
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Marek Wagner; Rolf Bjerkvig; Helge Wiig
et al. (2012). Inflamed tumor-associated adipose tissue is a depot for macrophages that stimulate tumor growth and angiogenesis. (external link)
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Majumi Kajimura; Helge Wiig; Rolf Kåre Reed
et al. (2001). Interstitial fluid pressure surrounding rat mesenteric venules during changes in fluid filtration. (external link)
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Helge Wiig; Tjøstolv Lund
(2001). Relationship between interstitial fluid volume and pressure (compliance) in hypothyroid rats. (external link)
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Knut Aukland; Olav Tenstad; Helge Wiig
(2001). Distribution spaces for hyaluronan and albumin in rat tail tendons. (external link)
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Olav Tenstad; Karin Johanne Heyeraas; Helge Wiig
et al. (2001). Drainage of plasma proteins from renal medullary interstitium in rats. (external link)
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Torbjørn Nedrebø; Rolf Kåre Reed; Roland Jonsson
et al. (2004). Differential cytokine response in interstitial fluid in skin and serum during experimental inflammation in rats. (external link)
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Marko Uutela; Maria Wirzenius; Karri Paavonen
et al. (2004). PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. (external link)
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Helge Wiig; Ellen Berggreen; Bengt Åge Sørby Borge
et al. (2004). Demonstration of altered signaling responses in bone marrow extracellular fluid during increased hematopoiesis in rats using a centrifugation method. (external link)
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Carl Erik Markhus; Helge Wiig
(2004). Isolation of interstitial fluid from skeletal muscle and subcutis in mice using a wick method. (external link)
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Marek Wagner; Eli Sihn Samdal Steinskog; Helge Wiig
(2019). Blockade of Lymphangiogenesis Shapes Tumor-Promoting Adipose Tissue Inflammation. (external link)
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Anca Virtej; Olav Tenstad; Helge Wiig
et al. (2020). Interstitial fluid drainage from rat apical area takes place via vessels in the mandibular canal.. (external link)
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Harald Kryvi; Iselin Rusten; Per Gunnar Fjelldal
et al. (2017). The notochord in Atlantic salmon (Salmo salar L.) undergoes profound morphological and mechanical changes during development. (external link)
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Frank Helle; Tine Veronica Karlsen; Olav Tenstad
et al. (2013). High-salt diet increases hormonal sensitivity in skin pre-capillary resistance vessels. (external link)
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Bert Inge Rosengren; Bengt Rippe; Olav Tenstad
et al. (2004). Acute peritoneal dialysis in rats results in a marked reduction of interstitial colloid osmotic pressure. (external link)
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Helge Wiig; Agnes Schroeder; Wolfgang Neuhofer
et al. (2013). Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. (external link)
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Hanne Haslene-Hox; Amina Madani; Kaja Christine Graue Berg
et al. (2014). Quantification of the concentration gradient of biomarkers between ovarian carcinoma interstitial fluid and blood. (external link)
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Panagiota Papadakou; Athanasia Bletsa; Mohammed Ahmed Alamin Yousif Yassin
et al. (2017). Role of Hyperplasia of Gingival Lymphatics in Periodontal Inflammation. (external link)
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Li-Hao Huang; Bernd H. Zinselmeyer; Chih-Hao Chang
et al. (2019). Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. (external link)
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Fitz-Roy E. Curry; Cecilie Brekke; Tine Veronica Karlsen
et al. (2010). Atrial natriuretic peptide modulation of albumin clearance and contrast agent permeability in mouse skeletal muscle and skin: role in regulation of plasma volume. (external link)
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Per Ole Iversen; Elvira Semaeva; Dag R. Sørensen
et al. (2009). Dendritic cells loaded with tumor antigens and a dual immunostimulatory and anti-IL-10 specific siRNA can prime T lymphocytes against leukemic cells. (external link)
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Bengt Åge Sørby Borge; Karl-Henning Kalland; Sue Olsen
et al. (2009). Cytokines are produced locally by myocytes in rat skeletal muscle during endotoxemia. (external link)
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Øyvind Sverre Svendsen; Malgorzata Barczyk; Svetlana Popova
et al. (2009). The alpha 11 beta 1 integrin has a mechanistic role in control of interstitial fluid pressure and edema formation in inflammation. (external link)
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David Michael Wright; Helge Wiig; C P Winlove
et al. (2003). Simultaneous measurement of interstitial fluid pressure and load in rat skin after strain application in vitro. (external link)
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Ellen Berggreen; Helge Wiig
(2013). Lymphangiogenesis and lymphatic function in periodontal disease. (external link)
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Marek Wagner; Rolf Bjerkvig; Helge Wiig
et al. (2013). Loss of adipocyte specification and necrosis augment tumor-associated inflammation. (external link)
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Lilian Ephrem Mkonyi; Athanasia Bletsa; Anne Isine Bolstad
et al. (2012). Gingival lymphatic drainage protects against porphyromonas gingivalis-induced bone loss in mice. (external link)
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Miro Julian Eigenmann; Tine Veronica Karlsen; Marek Wagner
et al. (2021). Pharmacokinetics and pharmacodynamics of t-cell bispecifics in the tumour interstitial fluid. (external link)
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Alf H. Øien; Olav Tenstad; Helge Wiig
(2024). Models of Hydration Dependent Lymphatic Opening, Interstitial Fluid Flows and Ambipolar Diffusion. (external link)
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Alf Hartvig Øien; Helge Wiig
(2016). Electrostatic, elastic and hydration-dependent interactions in dermis influencing volume exclusion and macromolecular transport. (external link)
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Rawad H Mounzer; Øyvind Sverre Svendsen; Peter Baluk
et al. (2010). Lymphotoxin-alpha contributes to lymphangiogenesis. (external link)
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Alf Hartvig Øien; Helge Wiig
(2018). Modeling In Vivo Interstitial Hydration-Pressure Relationships in Skin and Skeletal Muscle. (external link)
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Hege Kristin Brekke; Eystein Oveland; Odd Kolmannskog
et al. (2010). Isolation of interstitial fluid in skin during volume expansion: evaluation of a method in pigs. (external link)
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Simone P Niclou; Claude Danzeisen; Hans Petter Eikesdal
et al. (2008). A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions. (external link)
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Hans Jørgen Timm Guthe; Marianne Muller Indrebø; Torbjørn Nedrebø
et al. (2015). Interstitial fluid colloid osmotic pressure in healthy children. (external link)
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Tine Veronica Karlsen; Emmet Martin McCormack; Maja Mujic
et al. (2012). Minimally invasive quantification of lymph flow in mice and rats by imaging depot clearance of near-infrared albumin. (external link)
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Hanne Haslene-Hox; Eystein Oveland; Kaja Christine Graue Berg
et al. (2011). A new method for isolation of interstitial fluid from human solid tumors applied to proteomic analysis of ovarian carcinoma tissue. (external link)
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Matthias Hofmann; Emmet Martin McCormack; Maja Mujic
et al. (2009). Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumour model. (external link)
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Linda Mullins; Jessica Ivy; Mairi Ward
et al. (2021). Abnormal neonatal sodium handling in skin precedes hypertension in the SAME rat. (external link)
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Irene Matre Thowsen; Tine Veronica Karlsen; Elham Nikpey
et al. (2022). Na+ is shifted from the extracellular to the intracellular compartment and is not inactivated by glycosaminoglycans during high salt conditions in rats. (external link)
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Marko Uutela; Maria Wirzenius; Karri Paavonen
et al. (2004). PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. (external link)
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W. B. Zhang; Knut Aukland; T. Lund
et al. (2000). Distribution of interstitial fluid pressure and fluid volumes in hind-limb skin of rats: relation to meridians?. (external link)
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Helge Wiig; Rolf Kåre Reed; Olav Tenstad
(2000). Interstitial fluid pressure, composition of interstitium, and interstitial exclusion of albumin in hypothyroid rats. (external link)
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Daniela Negrini; Olav Tenstad; Helge Wiig
(2003). Interstitial exclusion of albumin in rabbit lung during development of pulmonary oedema. (external link)
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Daniela Negrini; Olav Tenstad; Helge Wiig
(2003). Interstitial exclusion of albumin in rabbit lung measured with the continuous infusion method in combination with the wick technique. (external link)
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Helge Wiig; Odd Kolmannskog; Olav Tenstad
et al. (2003). Effect of charge on interstitial distribution of albumin in rat dermis in vitro. (external link)
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Linda EB Stuhr; Alison Reith; Sigrid Lepsøe
et al. (2003). Fluid pressure in human dermal fibroblast aggregates measured with micropipettes. (external link)
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Helge Wiig; Knut Aukland; Olav Tenstad
(2003). Isolation of interstitial fluid from rat mammary tumors by a centrifugation method. (external link)
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Helge Wiig; Kristofer Rubin; Rolf Kåre Reed
(2003). New and active role of the interstitium in control of interstitial fluid pressure: potential therapeutic consequences. (external link)
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Christina Gyenge; Olav Tenstad; Helge Wiig
(2003). In vivo determination of steric and electrostatic exclusion of albumin in rat skin and skeletal muscle. (external link)
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Ellen Berggreen; Helge Wiig; Karin Johanne Heyeraas
(2003). Blood flow and interstitial fluid pressure in the rat submandibular gland during changes in perfusion. (external link)
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Tine Veronica Karlsen; Tore Reikvam; Anne Tofteberg
et al. (2017). Lymphangiogenesis Facilitates Initial Lymph Formation and Enhances the Dendritic Cell Mobilizing Chemokine CCL21 Without Affecting Migration. (external link)
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David Wright; Helge Wiig; Peter Winlove
et al. (2003). Simultaneous measurement of interstitial fluid pressure and load in rat skin after strain application in vitro. (external link)
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Alexei V. Salnikov; Nils-Erik Heldin; Linda Elin Birkhaug Stuhr
et al. (2006). Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma. (external link)
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Hanne Haslene-Hox; Eystein Oveland; Kathrine Woie
et al. (2013). Increased WD-repeat containing protein 1 in interstitial fluid from ovarian carcinomas shown by comparative proteomic analysis of malignant and healthy gynecological tissue. (external link)
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Carl Erik Nordvik Markhus; Tine Veronica Karlsen; Marek Wagner
et al. (2013). Increased interstitial protein because of impaired lymph drainage does not induce fibrosis and inflammation in lymphedema. (external link)
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Eli Sihn Samdal Steinskog; Kenneth Finne; Marianne Enger
et al. (2023). Isolation of lymph shows dysregulation of STAT3 and CREB pathways in the spleen and liver during leukemia development in a rat model. (external link)
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Andras Maifeld; Johannes Wild; Tine Veronica Karlsen
et al. (2021). Skin Sodium Accumulates in Psoriasis and Reflects Disease Severity. (external link)
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Daisuke Nakano; Kento Kitada; Ningning Wan
et al. (2020). Lipopolysaccharide induces filtrate leakage from renal tubular lumina into the interstitial space via a proximal tubular Toll-like receptor 4–dependent pathway and limits sensitivity to fluid therapy in mice. (external link)
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R Kvåle; RK Reed; Helge Wiig
et al. (1996). Iontoforese - gammelt prinsipp - nye bruksområder. (external link)
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Athanasia Bletsa; Ellen Berggreen; Inge Fristad
et al. (2006). Cytokine signalling in rat pulp interstitial fluid and transcapillary fluid exchange during lipopolysaccharide-induced acute inflammation. (external link)
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Helge Wiig
(2020). Commentary: Trends in cardiovascular medicine From deep in the heart - An emerging role of cardiac lymphatics. (external link)
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Alf Hartvig Øien; Sigrid Ravnsborg Justad; Olav Tenstad
et al. (2013). Effects of Hydration on Steric and Electric Charge-Induced Interstitial Volume Exclusion-a Model. (external link)
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Irene Matre Thowsen; Tore Reikvam; Trude Skogstrand
et al. (2022). Genetic engineering of lymphangiogenesis in skin does not affect blood pressure in mouse models of salt-sensitive hypertension. (external link)
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Hideharu Tanaka; T Lund; Helge Wiig
et al. (1999). High dose vitamin-C counteracts the negative interstitial fluid hydrostatic pressure and early edema generation in thermally injured rats. (external link)
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Amanda W. Lund; Marek Wagner; Manuel Fankhauser
et al. (2016). Lymphatic vessels regulate immune microenvironments in human and murine melanoma. (external link)
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Miro Julian Eigenmann; Tine Veronica Karlsen; Ben-Fillippo Krippendorff
et al. (2017). Interstitial IgG antibody pharmacokinetics assessed by combined in vivo- and physiologically-based pharmacokinetic modelling approaches. (external link)
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Eli Sihn Samdal Steinskog; Solfrid Johanne Sagstad; Marek Wagner
et al. (2016). Impaired lymphatic function accelerates cancer growth. (external link)
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Hideharu Tanaka; Tjøstolv Lund; Helge Wiig
et al. (1999). High dose Vitamin C counteracts the negative interstitial fluid hydrostatic pressure and early edema generation in thermally injured rats. (external link)
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Marianne Muller Indrebø; Ansgar Berg; Henrik Holmstrøm
et al. (2019). Fluid accumulation in the staged Fontan procedure: the impact of colloid osmotic pressures. (external link)
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Christian Hinze; Janett Ruffert; Katharina Walentin
et al. (2017). GRHL2 is required for collecting duct epithelial barrier function and renal osmoregulation. (external link)
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Rolf Kåre Reed; Kristofer Rubin; Helge Wiig
et al. (1992). Blockade of _b%b-Integrins in skin causes edema through lowering of interstitial fluid pressure. (external link)
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Li-Hao Huang; Bernd H. Zinselmeyer; Chih-Hao Chang
et al. (2018). Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. (external link)
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Matthias Hofmann; Maike Guschel; August Bernd
et al. (2006). Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model. (external link)
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Eystein Oveland; Tine Veronica Karlsen; Hanne Haslene-Hox
et al. (2012). Proteomic Evaluation of Inflammatory Proteins in Rat Spleen Interstitial Fluid and Lymph during LPS-Induced Systemic Inflammation Reveals Increased Levels of ADAMST1. (external link)
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Per Ole Iversen; Helge Wiig
(2005). Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis. (external link)
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Helge Wiig; Christina Gyenge; Olav Tenstad
(2005). The interstitial distribution of macromolecules in rat tumours is influenced by the negatively charged matrix components. (external link)
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Daniela Negrini; Olav Tenstad; Alberto Passi
et al. (2006). Differential degradation of matrix proteoglycans and edema development in rabbit lung. (external link)
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Helge Wiig; Olav Tenstad; Joel L. Bert
(2005). Effect of hydration on interstitial distribution of charged albumin in rat dermis in vitro. (external link)
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Tine Veronica Karlsen; Kari Alitalo; Marika J. Karkkainen
et al. (2006). Transcapillary fluid balance consequences of missing initial lymphatics studied in a mouse model of primary lymphoedema. (external link)
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Anne-Maj Samuelsson; Theda Ulrike Patricia Bartolomaeus; Harithaa Anandakumar
et al. (2023). VEGF-B hypertrophy predisposes to transition from diastolic to systolic heart failure in hypertensive rats. (external link)
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Hanne Haslene-Hox; Olav Tenstad; Helge Wiig
(2013). Interstitial fluid-a reflection of the tumor cell microenvironment and secretome. (external link)
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Lilian Ephrem Mkonyi; Athanasia Bletsa; Inge Fristad
et al. (2010). Importance of lymph vessels in transcapillary fluid balance in gingiva studied in a transgenic mouse model. (external link)
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Ellen Berggreen; Helge Wiig
(2006). Lowering of interstitial fluid pressure in rat submandibular gland: a novel mechanism in saliva secretion. (external link)
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Helge Wiig; Christina Gyenge; Per Ole Iversen
et al. (2008). The role of the extracellular matrix in tissue distribution of macromolecules in normal and pathological tissues: Potential therapeutic consequences. (external link)
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Aeksanteri Aspelund; Salli Antila; Steven Proulx
et al. (2015). A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules. (external link)
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Liliana Monica Bivol; Bjarne Magnus Iversen; Michael Hultström
et al. (2016). Unilateral renal ischaemia in rats induces a rapid secretion of inflammatory markers to renal lymph and increased capillary permeability. (external link)
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Ellen G. Avery; Hendrik Bartolomaeus; Andras Maifeld
et al. (2021). The Gut Microbiome in Hypertension: Recent Advances and Future Perspectives. (external link)
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Elham Nikpey Esfahlan; Tine Veronica Karlsen; Natalia Rakova
et al. (2017). High-salt diet causes osmotic gradients and hyperosmolality in skin without affecting interstitial fluid and lymph. (external link)
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Elvira Semaeva; Olav Tenstad; Athanasia Bletsa
et al. (2008). Isolation of rat trachea interstitial fluid and demonstration of local cytokine production in lipopolysaccharide-induced systemic inflammation. (external link)
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Elvira Semaeva; Olav Tenstad; Jørn Skavland
et al. (2010). Access to the spleen microenvironment through lymph shows local cytokine production, increased cell flux, and altered signaling of immune cells during lipopolysaccharide-induced acute inflammation. (external link)
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Solfrid Johanne Sagstad; Eystein Oveland; Tine Veronica Karlsen
et al. (2015). Extracellular matrix composition affects rat skin distribution volume of plasma proteins with different size and charge. (external link)
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Hanne Haslene-Hox; Eystein Oveland; Kathrine Woie
et al. (2015). Distribution volume of macromolecules in human ovarian and endometrial cancers - effects of extracellular matrix structure. (external link)
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Marek Wagner; Eli Sihn Samdal Steinskog; Helge Wiig
(2015). Adipose tissue macrophages: the inflammatory link between obesity and cancer? Invited review. (external link)
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Tommy A. Rehn; Bengt Åge Sørby Borge; Per K. Lunde
et al. (2009). Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats. (external link)
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Hans Jørgen Guthe; Torbjørn Nedrebø; Jan Kristian Damås
et al. (2018). Transcapillary fluid flux and inflammatory response during neonatal therapeutic hypothermia: An open, longitudinal, observational study. (external link)
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Helge Wiig; Olav Tenstad; Per Ole Iversen
et al. (2010). Interstitial fluid: the overlooked component of the tumor microenvironment?. (external link)
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Anca Virtej; Larissa Alexandrina von Marti; Marek Wagner
et al. (2024). Contribution of initial lymphatics to oral wound healing after tooth extraction. (external link)
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Bert-Inge Rosengren; Solfrid Johanne Sagstad; Tine Veronica Karlsen
et al. (2013). Isolation of interstitial fluid and demonstration of local proinflammatory cytokine production and increased absorptive gradient in chronic peritoneal dialysis. (external link)
Conference abstract
Research report
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Conference poster
Academic book chapter
Academic literature review
Master’s thesis
Non-fiction monograph
Conference lecture
Editorial/Leader article
See a complete overview of publications in NVA.