Academic article

• Achilleas Fardellas; Emelie Barreby; Madara Brice et al. (2026). ADAR1 Controls Macrophage Scavenging and Lipid‐Buffering Programs in Metabolic Tissues. (external link)
• Cristina Contreras; Ismael González-García; Patricia Seoane-Collazo et al. (2017). Reduction of hypothalamic endoplasmic reticulum stress activates browning of white fat and ameliorates obesity. (external link)
• Cristina Contreras; Francisco Gonzalez; Johan Fernø et al. (2015). The brain and brown fat. (external link)
• Begoña Porteiro; Marcos F. Fondevila; Teresa C. Delgado et al. (2017). Hepatic p63 regulates steatosis via IKK?/ER stress. (external link)
• Noelia Martínez-Sánchez; José M. Moreno-Navarrete; Cristina Contreras et al. (2017). Thyroid hormones induce browning of white fat. (external link)
• Ismael Gonzalez-Garcia; Cristina Contreras; Ánxela Estévez-Salguero et al. (2018). Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress. (external link)
• Pablo Blanco Martínez De Morentin; Ricardo Lage; Ismael Gonzalez-Garcia et al. (2015). Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-COA and the thermogenic effect of hypothalamic AMPK inhibition in female rats. (external link)
• Angela Fraga; Eva Rial-Pensado; Rubén Nogueiras et al. (2021). Activity-Based Anorexia Induces Browning of Adipose Tissue Independent of Hypothalamic AMPK. (external link)
• Atanaska Ivanova Doncheva; Frode Amador Norheim; Marit Hjorth et al. (2021). Serglycin Is Involved in Adipose Tissue Inflammation in Obesity. (external link)
• V. Pena-Leon; R. Perez-Lois; M. Villalon et al. (2023). Gastric GDF15 levels are regulated by age, sex, and nutritional status in rodents and humans. (external link)
• Regine Åsen Jersin; Divya Sri Priyanka Tallapragada; Andre Madsen et al. (2021). Role of the Neutral Amino Acid Transporter Slc7a10 in Adipocyte Lipid Storage, Obesity and Insulin Resistance. (external link)
• Maria J. Gonzalez-Rellan; Marcos F. Fondevila; Uxia Fernandez et al. (2021). O-GlcNAcylated p53 in the liver modulates hepatic glucose production. (external link)
• Audun Osland Vik-Mo; Johan Fernø; Silje Skrede et al. (2009). Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells. (external link)
• Daniel Beiroa; Monica Imbernon; Rosalía Gallego et al. (2014). GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK. (external link)
• Johan Fernø; Rosa Señaris; Carlos Diéguez et al. (2015). Orexins (hypocretins) and energy balance: More than feeding. (external link)
• Amparo Romero-Picó; Estrella Sanchez-Rebordelo; Monica Imbernon et al. (2018). Melanin-Concentrating Hormone acts through hypothalamic kappa opioid system and p70S6K to stimulate acute food intake. (external link)
• Martha Eimstad Haugstøyl; Martin Cornillet; Kristina Strand et al. (2022). Distinct T cell subsets in adipose tissue are associated with obesity. (external link)
• Audun Osland Vik-Mo; Astrid B. Birkenæs; Johan Fernø et al. (2008). Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. (external link)
• Teresa Maria Osland; Johan Fernø; Bjarte Håvik et al. (2011). Lithium differentially affects clock gene expression in serum-shocked NIH-3T3 cells. (external link)
• Patricia Seoane-Collazo; Pablo Blanco Martínez De Morentin; Johan Fernø et al. (2014). Nicotine improves obesity and hepatic steatosis and ER stress in diet-induced obese male rats. (external link)
• Astri Jeanette Meen; Atanaska Ivanova Doncheva; Yvonne Böttcher et al. (2023). Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue. (external link)
• Maria Therese Barøy Ræder; Johan Fernø; Audun Osland Vik-Mo et al. (2006). SREBP activation by antipsychotic- and antidepressant-drugs in cultured human liver cells: Relevance for metabolic side-effects?. (external link)
• Johan Fernø; Silje Skrede; Audun Osland Vik-Mo et al. (2006). Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs. (external link)
• Stephanie Le Hellard; Frank M. Theisen; Michael Haberhausen et al. (2009). Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?. (external link)
• Begoña Porteiro; Marcos F. Fondevila; Xabier Buque et al. (2018). Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis. (external link)
• Johan Fernø; Luis Varela; Silje Skrede et al. (2011). Olanzapine-induced hyperphagia and weight gain associate with crexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation. (external link)
• Johan Fernø; Silje Skrede; Audun Osland Vik-Mo et al. (2011). Lipogenic effects of psychotropic drugs: focus on the SREBP system. (external link)
• Ismael González-García; Johan Fernø; Miguel López (2017). Central oxytocin and energy balance: More than feelings. (external link)
• Valentina Capelli; Carmen Grijota-Martínez; Nathalia R. V. Dragano et al. (2021). Orally induced hyperthyroidism regulates hypothalamic amp-activated protein kinase. (external link)
• Monica Imbernon; Estrella Sanchez-Rebordelo; Amparo Romero-Picó et al. (2016). Hypothalamic kappa opioid receptor mediates both diet-induced and melanin concentrating hormone–induced liver damage through inflammation and endoplasmic reticulum stress. (external link)
• Silje Skrede; Ismael Gonzalez-Garcia; Luis Martins et al. (2017). Lack of ovarian secretions reverts the anabolic action of olanzapine in female rats. (external link)
• Goran Jassim; Silje Skrede; Maria Jesús Vázquez et al. (2012). Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat. (external link)
• Johan Fernø; Audun Osland Vik-Mo; Goran Jassim et al. (2009). Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver. (external link)
• Mar Quiñones; Johan Fernø; Carlos Dieguez et al. (2019). Exciting advances in GPCR-based drugs discovery for treating metabolic disease and future perspectives. (external link)
• Jessica Svärd; Therese Halvorsen Røst; Camilla Elise Nergård Sommervoll et al. (2019). Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice. (external link)
• Stephanie Le Hellard; Thomas W. Mühleisen; Srdjan Djurovic et al. (2010). Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples. (external link)
• Martha Haugstøyl; Martin Cornillet; Kristina Strand et al. (2023). Phenotypic diversity of human adipose tissue-resident NK cells in obesity. (external link)
• Kristina Strand; Natalie Stiglund; Martha Eimstad Haugstøyl et al. (2022). Subtype-specific surface proteins on adipose tissue macrophages and their association to obesity-induced insulin resistance. (external link)
• Mar Quiñones; Rene Hernandez-Bautista; Daniel Beiroa et al. (2021). Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner. (external link)
• Mar Quiñones; Omar Al-Massadi; Cintia Folgueira et al. (2018). p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1. (external link)
• Silvia Barja-Fernandez; Jose Maria Moreno-Navarrete; Cintia Folgueira et al. (2018). Plasma ANGPTL-4 is Associated with Obesity and Glucose Tolerance: Cross-Sectional and Longitudinal Findings. (external link)
• Silje Skrede; Vidar Martin Steen; Johan Fernø (2013). Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?. (external link)
• Silje Skrede; Johan Fernø; Maria Jesús Vázquez et al. (2012). Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats. (external link)
• Silje Skrede; Luis Martins; Rolf Kristian Berge et al. (2014). Olanzapine depot formulation in rat: a step forward in modelling antipsychotic-induced metabolic adverse effects. (external link)
• Mar Quiñones; Omar Al-Massadi; Rosalía Gallego et al. (2015). Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance. (external link)
• Goran Jassim; Johan Fernø; Frank M. Theisen et al. (2011). Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. (external link)
• Johan Fernø; Kari Merete Ersland; Inger Hødnebø Duus et al. (2015). Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain. (external link)
• Stephanie Le Hellard; F.M. Theisen; M Haberhausen et al. (2008). Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: pertubation of SREBP-controlled lipogenesis in drug-realted metabolic adverse effects?. (external link)
• Hans Jørgen Nielsen; Bjørn Gunnar Nedrebø; Alexander Fosså et al. (2022). Seven-year trajectories of body weight, quality of life and comorbidities following Roux-en-Y gastric bypass and sleeve gastrectomy. (external link)
• Natalie Stiglund; Kristina Strand; Martin Cornillet et al. (2019). Retained NK cell phenotype and functionality in non-alcoholic fatty liver disease. (external link)
• Maria Therese Barøy Ræder; Johan Fernø; Marte Glambek et al. (2006). Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells. (external link)
• Silje Skrede; Johan Fernø; Bodil Bjørndal et al. (2012). Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment. (external link)
• Patricia Seoane-Collazo; Johan Fernø; Francisco Gonzalez et al. (2015). Hypothalamic-autonomic control of energy homeostasis. (external link)
• Tone Nygaard Flølo; Alexander Fosså; Jonas Ingolf Petersson Nedkvitne et al. (2023). Long-term impact of gastropexy on use of acid-reducing medication, second operations for gastroesophageal reflux and subjective reflux symptoms after sleeve gastrectomy. (external link)
• Vidar Martin Steen; Silje Skrede; Tatiana Polushina et al. (2016). Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment. (external link)
• Johan Fernø; Maria Therese Barøy Ræder; Audun Osland Vik-Mo et al. (2005). Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?. (external link)
• Eva Tuduri; Daniel Beiroa; Johannes Stegbauer et al. (2016). Acute stimulation of brain mu opioid receptors inhibits glucose-stimulated insulin secretion via sympathetic innervation. (external link)
• Miriam Ejarque; Marianne Borlaug; Núria Vilarrasa et al. (2017). Angiopoietin-like protein 8/betatrophin as a new determinant of type 2 diabetes remission after bariatric surgery. (external link)
• Lisa Marie Dale Grymyr; Gunnar Mellgren; Adrian McCann et al. (2024). Preoperative risk factors associated with left ventricular dysfunction after bariatric surgery. (external link)
• S Le Hellard; TW Muhleisen; Srdjan Djurovic et al. (2008). Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples. (external link)
• Ricardo Lage; Claudia Parisi; Patricia Seoane-Collazo et al. (2015). Lack of hypophagia in CB1 null mice is associated to decreased Hypothalamic POMC and CART. (external link)
• Pablo B.Martinez de Morentin; Andrew J. Whittle; Johan Fernø et al. (2012). Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. (external link)
• AO Vik-Mo; Astrid Brate Birkenæs; J Fernø et al. (2008). Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. (external link)
• Oddrun Anita Gudbrandsen; Simon N Dankel; Lillian Skumsnes et al. (2019). Short-term effects of Vertical sleeve gastrectomy and Roux-en-Y gastric bypass on glucose homeostasis. (external link)
• Ismael González-García; Óscar Freire-Agulleiro; Naoki Nakaya et al. (2022). Olfactomedin 2 deficiency protects against diet-induced obesity. (external link)
• Cintia Folgueira; Daniel Beiroa; Aurelie Callon et al. (2016). Uroguanylin action in the brain reduces weight gain in obese mice via different efferent autonomic pathways. (external link)
• Patricia Seoane-Collazo; Amparo Romero-Picó; Eva Rial-Pensado et al. (2021). κ-opioid signaling in the lateral hypothalamic area modulates nicotine-induced negative energy balance. (external link)
• Ryoko Higa; Shirin Pourteymour; Pratibha Shrikant Kolan et al. (2025). Hepatic lipid metabolism is altered in Ubiad1+/- mice of both sexes. (external link)
• Ismael González-García; Pablo B. Martínez de Morentin; Ánxela Estévez-Salguero et al. (2018). mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol. (external link)

Academic literature review

• Sayani Mukherjee; Silje Skrede; Johan Fernø (2025). The hypothalamus as a therapeutic target: Towards novel approaches for managing antipsychotic-induced weight gain. (external link)
• Mar Quiñones; Omar Al-Massadi; Johan Fernø et al. (2014). Cross-talk between SIRT1 and endocrine factors: Effects on energy homeostasis. (external link)
• Omar Al Massadi; Miguel López; Johan Fernø et al. (2015). What is the real relevance of endogenous ghrelin?. (external link)
• Mar Quiñones; Eva Martínez-Grobas; Johan Fernø et al. (2021). Hypothalamic Actions of SIRT1 and SIRT6 on Energy Balance. (external link)
• Omar Al-Massadi; Paolo Parini; Johan Fernø et al. (2022). Metabolic actions of the growth hormone-insulin growth factor-1 axis and its interaction with the central nervous system. (external link)
• Eva Prida; Sara Álvarez-Delgado; Raquel Pérez-Lois et al. (2022). Liver Brain Interactions: Focus on FGF21 a Systematic Review. (external link)
• Ismael González-García; Johan Fernø; Carlos Diéguez et al. (2017). Hypothalamic Lipids: Key Regulators of Whole Body Energy Balance. (external link)
• Veronica Pena-Leon; Raquel Perez-Lois; Maria Villalon et al. (2024). Novel mechanisms involved in leptin sensitization in obesity. (external link)
• Sayani Mukherjee; Carlos Diéguez; Johan Fernø et al. (2023). Obesity wars: hypothalamic sEVs a new hope. (external link)
• Eva Prida; Sara Fernández-González; Verónica Pena-León et al. (2022). Crosstalk between Melanin Concentrating Hormone and Endocrine Factors: Implications for Obesity. (external link)
• Johan Fernø; Kristina Strand; Gunnar Mellgren et al. (2019). Natural killer cells as sensors of adipose tissue stress. (external link)
• Ricardo Lage; Johan Fernø; Rubén Nogueiras et al. (2016). Contribution of adaptive thermogenesis to the hypothalamic regulation of energy balance. (external link)
• Pablo Blanco Martínez De Morentin; Noelia Martinez-Sánchez; Juan Roa et al. (2014). Hypothalamic mTOR: the rookie energy sensor. (external link)
• Sayani Mukherjee; Silje Skrede; Martha Haugstøyl et al. (2023). Peripheral and central macrophages in obesity. (external link)
• Sayani Mukherjee; Silje Skrede; Edward Milbank et al. (2021). Understanding the Effects of Antipsychotics on Appetite Control. (external link)
• Noelia Martínez-Sánchez; CV Alvarez; Johan Fernø et al. (2014). Hypothalamic effects of thyroid hormones on metabolism. (external link)
• Omar Al-Massadi; Johan Fernø; Carlos Dieguez et al. (2019). Glucagon control on food intake and energy balance. (external link)
• Eva Tuduri; Monica Imbernon; Rene Javier Hernández-Bautista et al. (2017). Gpr55: A new promising target for metabolism?. (external link)
• Nathalia R.V. Dragano; Johan Fernø; Carlos Diéguez et al. (2020). Reprint of: Recent Updates on Obesity Treatments: Available Drugs and Future Directions. (external link)
• Mar Quiñones; Johan Fernø; Omar Al-Massadi (2020). Ghrelin and liver disease. (external link)
• Nathalia R.V. Dragano; Johan Fernø; Carlos Diéguez et al. (2020). Recent Updates on Obesity Treatments: Available Drugs and Future Directions. (external link)

Conference lecture

• Tone Nygaard Flølo; Alexander Fosså; Jo Erling Riise Waage et al. (2023). Long-term impact of gastropexy on use of acid-reducing medication, second operations for gastroesophageal reflux and subjective reflux symptoms after sleeve gastrectomy. (external link)

Conference poster

• Erik Wilhelm Vinnes; Kristin Moberg Aakre; Johan Fernø et al. (2024). Long-term effect of bariatric surgery on circulating GDF15 concentrations. (external link)
• Johan Fernø; Aron Willems; Simon N Dankel et al. (2014). SLC7A10, a novel adipocyte-enriched gene with a potential role in adipocyte differentiation. (external link)

Conference abstract

• Audun Osland Vik-Mo; Johan Fernø; Maria Ræder et al. (2006). Antipsychotic and antidepressive drugs regulate the expression of apolipoprotein E. (external link)
• Johan Fernø; Audun Osland Vik-Mo; Goran Jassim et al. (2008). Effect of clozapine on memory function in the hippocampal lesion model of schizophrenia. (external link)
• Audun Osland Vik-Mo; Johan Fernø; Vidar Martin Steen (2008). Differential effects of antipsychotic drugs on ATP-binding cassette type A1 (ABCA1) and apolipoprotein E (ApoE) gene expression in cultured cells. (external link)
• Audun Osland Vik-Mo; Astrid B. Birkenæs; Johan Fernø et al. (2007). Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. (external link)

Popular science article

• Martha Eimstad Haugstøyl; Johan Fernø (2017). GPR55 - en ny reseptor for behandling av metabolsk sykdom?. (external link)

Doctoral thesis (PhD)

• Johan Fernø; Vidar Martin Steen (2007). Lipogenic effects of antipsychotic drugs in cultured cells and in rat. (external link)

Editorial/Leader article

• Silje Skrede; Johan Fernø; Vidar Martin Steen (2013). Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?. (external link)

See a complete overview of publications in NVA.