Publications
Doctoral thesis (PhD)
Academic article
- June Helen Gudmestad; Lucas Unger; Joao A Paulo et al. (2025). Endocrine-disrupting chemical exposure during differentiation alters the proliferation–maturation balance in stem-cell islets. (external link)
- Shayla Sharmine; Thomas Aga Legøy; Lucas Unger et al. (2025). Caloric Restriction Substantially Improves Glucose Regulation in Mice With Hnf1a‐Deficient Beta‐Cells. (external link)
- Lucas Unger; Ulrik Larsen; Shayla Sharmine et al. (2025). Efficient cytoplasmic cell quantification using a semi-automated FIJI-based tool. (external link)
- Andreas Frøslev Mathisen; Andrei Mircea Vacaru; Lucas Unger et al. (2024). Molecular profiling of NOD mouse islets reveals a novel regulator of insulitis onset. (external link)
- Andreas Frøslev Mathisen; Thomas Aga Legøy; Ulrik Larsen et al. (2024). The age-dependent regulation of pancreatic islet landscape is fueled by a HNF1a-immune signaling loop. (external link)
- Lucas Unger; Luiza Mihaela Ghila; Simona Chera (2024). Targeted Gene Silencing by Using GapmeRs in Differentiating Human-Induced Pluripotent Stem Cells (hiPSC) Toward Pancreatic Progenitors. (external link)
- Lucas Unger; Andreas Frøslev Mathisen; Simona Chera et al. (2024). The GLI code controls HNF1A levels during foregut differentiation. (external link)
- Jakub Vasicek; Ksenia Kuznetsova; Dafni Skiadopoulou et al. (2024). ProHap enables human proteomic database generation accounting for population diversity. (external link)
- Andreas Frøslev Mathisen; Ulrik Larsen; Natalie Aasen Kavli et al. (2024). Moderate beta-cell ablation triggers synergic compensatory mechanisms even in the absence of overt metabolic disruption. (external link)
Lecture
- Thomas Aga Legøy; Andreas Frøslev Mathisen; Joao Paulo et al. (2024). Impact of diabetogenic signals from endocrine disrupting chemicals on a HNF1A cell model. (external link)
- Lucas Unger; Thomas Aga Legøy; Luiza Mihaela Ghila et al. (2023). Exploring the role of transcription factors HNF1A, HNF1B, and HNF4A in human induced pluripotent stem cell-derived pancreatic islet cell differentiation. (external link)
- Lucas Unger; Thomas Aga Legøy; Simona Chera et al. (2023). Exploring the role of transcription factors HNF1A, HNF1B, and HNF4A in human pancreatic islet cell differentiation. (external link)
Conference poster
- Lucas Unger; Andreas Frøslev Mathisen; Thomas Aga Legøy et al. (2024). Deciphering the HNF1A and Hedgehog Signaling Crosstalk during Stem Cell Islet differentiation. (external link)
- Lucas Unger; Thomas Aga Legøy; Luiza Mihaela Ghila et al. (2024). Exploring hedgehog signaling and HNF1A Crosstalk in HNF1A-MODY stem cell islets. (external link)
- Lucas Unger; Thomas Aga Legøy; Andreas Frøslev Mathisen et al. (2023). Investigating the developmental role of HNF1A, HNF1B and HNF4A in human pancreatic islet cell differentiation. (external link)
- Ulrik Larsen; Andreas Frøslev Mathisen; Natalie Aasen Kavli et al. (2024). Investigating stress-induced islet cell proliferation following partial insulin-secreting β-cell ablation in mice. (external link)
- Thomas Aga Legøy; Lucas Unger; Joao A. Paulo et al. (2024). Exposure to Endocrine Disrupting Chemicals During Differentiation of HNF1A-MODY SC-islets has an Adverse Effect on Cell Fitness. (external link)
- Lucas Unger; Thomas Aga Legøy; Luiza Mihaela Ghila et al. (2022). Investigating the developmental role of HNF1A in human pancreatic islet cell differentiation. (external link)
- Thomas Aga Legøy; Andreas Frøslev Mathisen; Joao Paulo et al. (2023). Human induced pluripotent stem cells as a model for environmental impact on diabetes. (external link)
- Lucas Unger; Luiza Mihaela Ghila; Simona Chera (2022). Investigating the developmental role of HNF1A, HNF1B and HNF4A in human pancreatic islet cell differentiation. (external link)