Vitenskapelig artikkel

• Simon Ulvenes Kverneng; Sepideh Mostafavi; Yana Mikhaleva et al. (2025). Platelet mitochondrial complex I and IV activities are not reliable stratification biomarkers in Parkinson's disease. (ekstern lenke)
• Christian Dølle; Marc Niere; Emilia Lohndal et al. (2010). Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation. (ekstern lenke)
• Irene Flønes; Lilah Toker; Dagny Ann Sandnes et al. (2024). Mitochondrial complex I deficiency stratifies idiopathic Parkinson’s disease. (ekstern lenke)
• Veronika Kulikova; Konstantin Shabalin; Kirill Nerinovski et al. (2015). Generation, release, and uptake of the NAD precursor nicotinic acid riboside by human cells. (ekstern lenke)
• Irene Hana Flønes; Pawel Szymon Sztromwasser; Kristoffer Haugarvoll et al. (2016). Novel SLC19A3 promoter deletion and allelic silencing in biotin-thiamine-responsive basal ganglia encephalopathy. (ekstern lenke)
• Christian Dölle; Irene Hana Flønes; Gonzalo Sanchez Nido et al. (2016). Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease. (ekstern lenke)
• Nelson Uchechukwu Osuagwu; Christian Dölle; Charalampos Tzoulis (2019). Poly-ADP-ribose assisted protein localization resolves that DJ-1, but not LRRK2 or α-synuclein, is localized to the mitochondrial matrix. (ekstern lenke)
• Brage Brakedal; Christian Dölle; Frank Riemer et al. (2022). The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease. (ekstern lenke)
• Irene Hana Flønes; Gerda Ricken; Sigrid Klotz et al. (2020). Mitochondrial respiratory chain deficiency correlates with the severity of neuropathology in sporadic Creutzfeldt-Jakob disease. (ekstern lenke)
• Christian Dölle; Mathias Ziegler (2017). ADP-ribosylation of DNA moving into focus. (ekstern lenke)
• Fiona Dick; Gonzalo Sanchez Nido; Guido Werner Alves et al. (2020). Differential transcript usage in the Parkinson’s disease brain. (ekstern lenke)
• Christian Dölle; Laurence Bindoff; Charalampos Tzoulis (2018). 3,3'-Diaminobenzidine staining interferes with PCR-based DNA analysis. (ekstern lenke)
• Johannes Jernqvist Gaare; Gonzalo Sanchez Nido; Christian Dölle et al. (2020). Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci. (ekstern lenke)
• Lena Elise Høyland; Magali R Van Linden; Marc Niere et al. (2024). Subcellular NAD+ pools are interconnected and buffered by mitochondrial NAD+. (ekstern lenke)
• Nick R. Love; Nadine Pollak; Christian Dölle et al. (2015). NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms. (ekstern lenke)
• Johannes Jernqvist Gaare; Christian Dölle; Brage Brakedal et al. (2023). Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson's disease. (ekstern lenke)
• Simon Ulvenes Kverneng; Kjersti Eline Stige; Haakon Berven et al. (2025). Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson’s disease. (ekstern lenke)
• Daniela Buonvicino; Francesca Mazzola; Federica Zamporlini et al. (2018). Identification of the Nicotinamide Salvage Pathway as a New Toxification Route for Antimetabolites. (ekstern lenke)
• Andrey Nikiforov; Christian Dølle; Marc Niere et al. (2011). Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells FROM ENTRY OF EXTRACELLULAR PRECURSORS TO MITOCHONDRIAL NAD GENERATION. (ekstern lenke)
• Magali R Van Linden; Marc Niere; Andrey Nikiforov et al. (2017). Compartment-Specific Poly-ADP-Ribose Formation as a Biosensor for Subcellular NAD Pools. (ekstern lenke)
• Corinna Lau; Christian Dølle; Toni I. Gossmann et al. (2010). Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases. (ekstern lenke)
• Brage Brakedal; Irene Hana Flønes; Simone B. C. Frizell Reiter et al. (2017). Glitazone use associated with reduced risk of Parkinson's disease. (ekstern lenke)
• Haakon Berven; Simon Ulvenes Kverneng; Erika Sheard et al. (2023). NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease. (ekstern lenke)
• Gonzalo Sanchez Nido; Martina Galatea Castelli; Sepideh Mostafavi et al. (2024). Single-nucleus transcriptomics reveals disease- and pathology-specific signatures in α-synucleinopathies. (ekstern lenke)
• Gonzalo Sanchez Nido; Christian Dölle; Irene Hana Flønes et al. (2018). Ultradeep mapping of neuronal mitochondrial deletions in Parkinson's disease. (ekstern lenke)
• Renate Hvidsten Skoge; Christian Dölle; Mathias Ziegler (2014). Regulation of SIRT2-dependent α-tubulin deacetylation by cellular NAD levels. (ekstern lenke)
• Irene Hana Flønes; Erika Fernandez-Vizarra; Maria Lykouri et al. (2017). Neuronal complex I deficiency occurs throughout the Parkinson's disease brain, but is not associated with neurodegeneration or mitochondrial DNA damage. (ekstern lenke)
• Marc Niere; Masato Mashimo; Line Agledal et al. (2012). ADP-ribosylhydrolase 3 (ARH3), not poly(ADP-ribose)glycohydrolase (PARG) isoforms, is responsible for degradation of mitochondrial matrix-associated poly(ADP-ribose). (ekstern lenke)
• Lilah Toker; Gia T. Tran; Janani Sundaresan et al. (2021). Genome-wide histone acetylation analysis reveals altered transcriptional regulation in the Parkinson’s disease brain. (ekstern lenke)
• Fiona Dick; Gard Aasmund Skulstad Johanson; Ole-Bjørn Tysnes et al. (2024). Brain Proteome Profiling Reveals Common and Divergent Signatures in Parkinson’s Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy. (ekstern lenke)
• Magali R Van Linden; Christian Dölle; Ina Katrine Nitschke Pettersen et al. (2015). Subcellular distribution of NAD+ between cytosol and mitochondria determines the metabolic profile of human cells. (ekstern lenke)
• Romain Guillaume Bernard Guitton; Christian Dölle; Guido Werner Alves et al. (2022). Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA. (ekstern lenke)

Vitenskapelig litteraturgjennomgang

• Nadine Pollak; Christian Dølle; Mathias Ziegler (2007). The power to reduce: pyridine nucleotides - small molecules with a multitude of functions. (ekstern lenke)
• Christian Dölle; Renate Hvidsten Skoge; Magali R Van Linden et al. (2013). NAD biosynthesis in humans - enzymes, metabolites and therapeutic aspects. (ekstern lenke)
• Kjersti Eline Stige; Simon Ulvenes Kverneng; Soumya Sharma et al. (2024). The STRAT-PARK cohort: A personalized initiative to stratify Parkinson's disease. (ekstern lenke)
• Christian Dölle; Charalampos Tzoulis (2025). NAD augmentation as a disease-modifying strategy for neurodegeneration. (ekstern lenke)
• Alberto Chiarugi; Christian Dølle; Roberta Felici et al. (2012). The NAD metabolome - a key determinant of cancer cell biology. (ekstern lenke)
• Christian Dölle; Johannes Gregor M Rack; Mathias Ziegler (2013). NAD and ADP-ribose metabolism in mitochondria. (ekstern lenke)

Konferanseposter

• Line Agledal; Christian Dølle; Mathias Ziegler (2008). Alteration of isoform-specific NMNAT expression by reduction of subcellular NAD pools. (ekstern lenke)
• Line Agledal; Marc Niere; Christian Dølle et al. (2007). Expression of NAD biosynthetic enzymes in response to decreased mitochondrial and cytosolic NAD levels. (ekstern lenke)
• Christian Dølle (2005). A new potential ADP-ribose acceptor protein in mitochondria. (ekstern lenke)
• Christian Dølle (2005). A new potential ADP-ribose acceptor protein in mitochondria. (ekstern lenke)

Konferanseabstrakt

• V Livinskaya; A Afanasyeva; Christian Dölle et al. (2013). Potential role of cytosolic 5'- nucleotidases in human NAD metabolism. (ekstern lenke)

Konferanseforedrag

• Marc Niere; Christian Dølle; Line Agledal et al. (2010). Dissection of candidate enzymes involved in mitochondrial poly-ADP-ribose degradation. (ekstern lenke)
• Line Agledal; Christian Dølle; Mathias Ziegler (2009). Alteration of compartment-specific NAD biosynthesis by reduction of individual subcellular NAD pools. (ekstern lenke)
• Christian Dølle; Gennaro Agrimi; Ferdinando Palmieri et al. (2012). Identification of the pathways generating organellar NAD pools using targeted poly-ADP ribose formation. (ekstern lenke)
• Christian Dølle (2007). Visualization of an enzymatic activity to determine the suborganellar location of mitochondrial proteins. (ekstern lenke)

Doktorgradsavhandling

• Irene Hana Flønes; Charalampos Tzoulis; Christian Dölle et al. (2019). Mitochondrial mechanisms in neurodegeneration. (ekstern lenke)

Lederartikkel

• Christian Dølle; Mathias Ziegler (2009). Application of a coupled enzyme assay to characterize nicotinamide riboside kinases. (ekstern lenke)

Masteroppgave

• Nelson Uchechukwu Osuagwu; Charalampos Tzoulis; Christian Dölle (2017). High-resolution subcellular localization of pathogenic proteins in Parkinson's disease. (ekstern lenke)

Se en fullstendig oversikt over publikasjoner i NVA.